Inhibitors of farnesyl-protein transferase

Details Inhibitors of farnesyl-protein transferase Inhibitors of farnesyl-protein transferase

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/55 (2006.01) C07D 243/24 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2250203

The present invention is directed to substituted benzodiazepine compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

La présente invention concerne des dérivés de substitution de la benzodiazépine, inhibiteurs de la farnésyle-protéine transférase (FTase), ainsi que la farnésylation de la protéine oncogène Ras. L'invention concerne enfin des compositions chimiothérapeutiques qui renferment les composés de la présente invention, les méthodes permettant d'inhiber la farnésyl-protéine transférase, et la farnésylation de la protéine oncogène Ras.

Affiliated with

Also associated with

Rating

Inhibitors of farnesyl-protein transferase does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibitors of farnesyl-protein transferase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors of farnesyl-protein transferase will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1877288