Conjugated mucin peptide vaccines

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/385 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2249395

This invention provides a vaccine capable of producing an immune response which recognizes a mucin, comprising an amount of mucin peptide conjugated to an immunogenic protein effective to stimulate or enhance immune response in the subject, an effective amount of an adjuvant and a pharmaceutically acceptable vehicle. This invention further provides a method for stimulating or enhancing production of an immune response which recognizes a mucin, comprising administering to the subject the above-described vaccine.

Vaccin susceptible de produire une réaction immunitaire qui reconnaît une mucine, comprenant une certaine quantité de peptide de mucine conjugué avec une protéine immunogène qui stimule ou accroît la réaction immunitaire du sujet, une quantité efficace d'un adjuvant et un excipient acceptable sur le plan pharmaceutique. L'invention porte aussi sur une technique de stimulation ou d'augmentation de la production d'une réaction immunitaire qui reconnaît une mucine, comprenant l'administration au sujet du vaccin décrit ci-dessus.

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