Methylphenidate solution and associated methods of...

A - Human Necessities – 61 – K

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A61K 47/12 (2006.01) A61K 9/08 (2006.01) A61K 31/4458 (2006.01)

Patent

CA 2540052

A methylphenidate solution and associated methods of administration and production, which includes methylphenidate and at least one organic acid dissolved in a solvent system, where the solvent system includes at least one non-aqueous solvent. The solvent system may include water. The non-aqueous solvent can include, but is not limited to polyols and glycols and associated mixtures thereof. Pharmaceutical additives such as flavorings, colorants, buffers, preservatives and mixtures thereof may be optionally added to the methylphenidate solution.

L'invention concerne une solution de méthylphénidate et des procédés associés d'administration et de production. Cette solution comprend du méthylphénidate et au moins un acide organique dissous dans un système de solvants, ce système de solvants comprenant au moins un solvant non aqueux. Ledit système de solvants peut contenir de l'eau. Le solvant non aqueux peut comprendre, de façon non limitative, des polyols et des glycols et des mélanges associés de ceux-ci. Des additifs pharmaceutiques, tels que des aromatisants, des colorants, des tampons, des conservateurs et des mélanges de ceux-ci, peuvent être ajoutés éventuellement à la solution de méthylphénidate.

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