Pyrimidine-2,4-diamines and their uses

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 498/04 (2006.01) A61K 31/5383 (2006.01) A61P 35/00 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2630357

The present invention relates to diaryl pyrimidine-2,4-diamines, pharmaceutical compositions thereof, and the use of the compounds and compositions for the inhibition of kinases. The compounds, analogs, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions can be used in the treatment and prevention of cancer.

La présente invention concerne des pyrimidine-2,4-diamines diaryles, des compositions pharmaceutiques de celles-ci et l'utilisation des composés et des compositions pour l'inhibition de kinases. Les composés, des analogues et leurs sels pharmaceutiquement acceptables ainsi que les compositions pharmaceutiques peuvent être utilisés pour le traitement et la prévention du cancer.

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