Rapid preparation and use of engineered tissue and scaffolds...

A - Human Necessities – 61 – L

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A61L 27/38 (2006.01)

Patent

CA 2748147

The present invention relates to methods, technical apparatus and compositions to achieve short term processing for the manufacture of a graft or transplant in form of a scaffold that can be used to treat or to heal injuries and traumas of a great diversity of tissues and organs in a central or peripheral location of the human or animal body. The invention specifically relates to tissue regeneration by means of stem cells and different specific tissue and organ repair promoting factors that activate said endogenous or exogenous stem cells to differentiate to specific tissue cells thus reconstituting the original microenvironment of the cell damaged by the injury.

La présente invention concerne des procédés, un appareil technique et des compositions pour réaliser le traitement de courte durée pour la fabrication d'un greffon ou d'une greffe sous la forme d'un échafaudage qui peut être utilisé pour traiter, soigner des lésions ou des traumatismes d'une grande variété de tissus et d'organes dans un site central ou périphérique du corps humain ou animal. De manière spécifique, l'invention concerne la régénération tissulaire au moyen de cellules souches et de différents facteurs promoteurs de réparation de tissus et d'organes spécifiques qui activent lesdites cellules souches endogènes et exogènes pour les différencier en des cellules tissulaires spécifiques permettant ainsi la reconstitution du microenvironnement d'origine de la cellule endommagée par une lésion.

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