Hydrophilic membranes with a non-ionic surfactant

Details Hydrophilic membranes with a non-ionic surfactant Hydrophilic membranes with a non-ionic surfactant

B - Operations, Transporting

01

D

B01D 71/06 (2006.01) B01D 67/00 (2006.01) B01D 69/00 (2006.01) B01D 71/68 (2006.01)

Patent

CA 2699724

The invention relates to hydrophilic membranes which are supplemented or treated with a non-ionic surfactant and processes for preparing such membranes. The membranes are particularly suitable for plasma separation or for haemodialysis and haemodiafiltration, but can also advantageously be used in other applications. Accordingly, the invention is further directed to the use of such membranes for plasma separation, plasma filtration, micro filtration, plasma therapy, haemodialysis and haemodiafiltration or cell filtration applications, respectively. The treated hydrophilic membranes show excellent biocompatibility, such as reduced platelet drop and decreased TAT levels.

La présente invention concerne des membranes hydrophiles qui sont additionnées d'un tensioactif non ionique ou traitées au moyen d'un tel tensioactif, ainsi que leurs procédés de préparation. Ces membranes sont particulièrement adaptées à la séparation du plasma ou à l'hémodialyse et à l'hémodiafiltration, mais peuvent également être avantageusement utilisées dans d'autres applications. En conséquence, l'invention concerne, en outre, l'utilisation desdites membranes pour des applications en matière de, respectivement, séparation du plasma, filtration du plasma, microfiltration, thérapie plasmatique, hémodialyse et hémodiafiltration ou encore filtration cellulaire. Les membranes hydrophiles traitées présentent une remarquable biocompatibilité, se traduisant, par exemple, par une baisse de la chute du nombre de plaquettes, ainsi que des niveaux TAT.

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