A - Human Necessities – 61 – B
Patent
A - Human Necessities
61
B
A61B 6/00 (2006.01) G01N 21/64 (2006.01) G01N 33/50 (2006.01) G01N 33/533 (2006.01) A61B 5/00 (2006.01)
Patent
CA 2402233
Methods useful in detecting abnormal cells and tissues based upon measurement of tryptophan-associated autofluorescence are disclosed. The methods involve exposing cells to ultraviolet light; measuring autofluorescence at a wavelength indicative of tryptophan emission; and determining that the cells constitute abnormal tissue of emission intensity exceeds that of normal cells. The methods can detect and distinguish abnormal cell development in metaplasia, hyperplasia, dysplasia and cancer. The method also detects the presence of inflammation.
Procédé utile dans la détection de cellules et tissus anormaux, fondé sur la mesure de l'autofluorescence associée à tryptophane. Les procédés consistent à exposer les cellules à la lumière ultraviolette, mesurer l'autofluorescence à une longueur d'onde indiquant l'émission de tryptophane et déterminer si les cellules constituant le tissu à intensité d'émission anormale sont plus nombreuses que les cellules normales. Le procédé permet de détecter et de distinguer le développement de cellules anormales en cas de métaplasie, hyperplasie, dysplasie et de cancer. Le procédé permet aussi de détecter la présence d'une inflammation.
Banerjee Bhaskar
Osler Hoskin & Harcourt Llp
LandOfFree
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