Therapeutic use of anti-cs1 antibodies

Details Therapeutic use of anti-cs1 antibodies Therapeutic use of anti-cs1 antibodies

A - Human Necessities

61

K

A61K 39/395 (2006.01)

Patent

CA 2561065

The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen- binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.

L'invention concerne des antagonistes du CS1 qui fixent et neutralisent au moins une activité biologique du CS1. L'invention concerne également une composition pharmaceutique comprenant lesdits anticorps ou des fragments de liaison antigènes. L'invention concerne, de plus, un procédé pour prévenir ou traiter des états pathologiques, notamment des troubles immuns et le cancer, chez un sujet nécessitant le traitement, comprenant l'administration chez le sujet d'une quantité efficace desdits antagonistes.

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