C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/078 (2010.01) C12N 5/0783 (2010.01) A01N 63/00 (2006.01) A61K 35/14 (2006.01) A61K 39/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01)
Patent
CA 2682527
The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing at least one of an antigen- recognizing receptor and a co-stimulatory ligand and methods of use therefore for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired.
La présente invention concerne des cellules immunosensibles, y compris des lymphocytes T, des lymphocytes T cytotoxiques, des lymphocytes T régulateurs, et des cellules tueuses naturelles (NK), exprimant au moins un récepteur reconnaissant un antigène et un ligand costimulant. L'invention concerne également des procédés d'utilisation de celles-ci dans le traitement de la néoplasie et d'autres pathologies dans lesquelles une augmentation de la réponse immunitaire spécifique à l'antigène est souhaitée.
Sadelain Michael
Stephan Mattias
Gowling Lafleur Henderson Llp
Memorial Sloan-Kettering Cancer Center
LandOfFree
Constitutive expression of costimulatory ligands on... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Constitutive expression of costimulatory ligands on..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Constitutive expression of costimulatory ligands on... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1882561