Immunogenic cancer proteins and peptides and method of use

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 39/00 (2006.01) C07K 1/113 (2006.01) C07K 7/04 (2006.01) C07K 14/705 (2006.01) C07K 14/82 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2160713

The present invention relates to tumor specific antigens and functional proteins of a tumor cell preparable by identifying proteins present in the tumor cell that are selectively immunogenic for tumor patients. The present invention still further provides a process of making a peptide library of tumor specific humoral antigens, a process of increasing the immunogenic specificity of a tumor-associated antigen, an assay kit for detecting the presence of an antibody immunoreactive with a tumor-specific antigen, and a process of making T cells sensitized to a tumor-specific antigen.

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