Methods and compositions for increasing tissue tropism of...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/861 (2006.01)

Patent

CA 2658805

Methods, compositions and uses are provided for increasing the tissue tropism of recombinant adenoviruses comprising using recombinant cells that provide to the recombinant adenovirus a second fibre, thereby altering the tropism of the recombinant adenovirus.

L'invention concerne des procédés permettant de préparer des vecteurs d'adénovirus présentant un tropisme modifié. L'invention concerne également des compositions contenant ces vecteurs et leurs procédés d'utilisation.

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