Microrna expression profile associated with pancreatic cancer

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07H 21/02 (2006.01)

Patent

CA 2638844

Methods are provided for diagnosing whether a subject has, or is at risk of developing, pancreatic cancer. The methods include measuring the level of at least one miR gene product in a biological sample derived from the subject's pancreas. An alteration in the level of the miR gene product in the biological sample as compared to the level of a corresponding miR gene product in a control sample, is indicative of the subject either having, or being at risk for developing, pancreatic cancer.

L'invention concerne des procédés pour diagnostiquer la présence ou le risque du cancer de pancréas chez un sujet. Les procédés comprennent la mesure des taux d'au moins un produit génique miR dans un échantillon biologique dérivé du pancréas d'un sujet. Une altération du taux de produit génique miR dans l'échantillon biologique en comparaison au taux de produit génique miR dans un échantillon de référence indique la présence ou le risque du cancer de pancréas chez le sujet.

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