Synthesis of nicotinic analogs useful for the treatment of...

Details Synthesis of nicotinic analogs useful for the treatment of... Synthesis of nicotinic analogs useful for the treatment of...

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/445 (2006.01) A61K 31/4545 (2006.01) A61K 31/455 (2006.01)

Patent

CA 2362719

A novel pharmaceutical composition for use as an anti-neurodegenerative agent, comprising anabaseine, DMAB-anabaseine or anabasine in combination with a pharmaceutically acceptable carrier, the anabaseine having the general chemical structure: (See formula I) and the anabaseine, DMAB-anabaseine or anabasine also known by the following respective chemical formulae: 2-(3-pyridyl)-3,4,5,6-tetrahydropyridine, 3-[p- (dimethylamino) benzylidene]-3,4,5,6-tetrahydro-2,3'-bypyridine, and 2-(3-pyridyl) piperidine. A novel method of making an anabaseine-based pharmaceutical composition is also disclosed.

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