The neurotrophic factor nnt-1

Details The neurotrophic factor nnt-1 The neurotrophic factor nnt-1

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A01K 67/027 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01) C07K 16/22 (2006.01) C12N 1/21 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2279999

Disclosed are nucleic acids encoding novel neurotrophic factors designated NNT- 1. Also disclosed are amino acid sequences for NNT-1 polypeptides, methods for preparing NNT-1 polypeptides, and other related aspects. Such polypeptides are active in stimulating B-cell and/or T cell production, as well as reducing inflammatory responses.

L'invention concerne des acides nucléiques codant de nouveaux facteurs neurotrophiques, désignés NNT-1. L'invention concerne également des séquences d'acides aminés destinées aux polypeptides NNT-1, des méthodes de préparation de polypeptides NNT-1 et d'autres aspects liés. Ces polypeptides présentent une activité stimulant la production de cellules B et/ou de cellules T et réduisant les réactions inflammatoires.

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