C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61P 25/00 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2507055
The invention relates to the use of an agent such as an antibody capable of reacting with PrP in the prevention of prion replication in a subject, in the treatment or prevention of prion infection, in the treatment or prevention of neuropathology associated with prion infection or in the preparation of a medicament for the treatment or prevention of prion disease. Furthermore, the invention relates to methods of treatment of prion disease, methods of inhibiting prion replication and antibodies for use in such methods.
L'invention concerne l'utilisation d'un agent, tel qu'un anticorps capable de réagir avec la protéine du prion (PrP), dans la prévention de la réplication du prion chez un sujet, dans le traitement ou la prévention de l'infection par le prion, dans le traitement ou la prévention de la neuropathologie associée à l'infection par le prion ou dans la préparation d'un médicament pour le traitement ou la prévention de la maladie du prion. En outre, cette invention concerne des méthodes de traitement de la maladie du prion, des méthodes d'inhibition de la réplication du prion ainsi que des anticorps destinés à être utilisés dans lesdites méthodes.
Collinge John
Hawke Simon
D-Gen Limited
Gowling Lafleur Henderson Llp
Medical Research Council
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