C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/071 (2010.01) A61K 31/713 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 17/02 (2006.01) C12N 15/00 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12P 21/00 (2006.01)
Patent
CA 2676143
The presently disclosed subject matter provides modified cell-derived exosomes substantially lacking one or more immunosuppressive polypeptides. The presently-disclosed subject matter further provides methods of producing the modified exosomes and methods of using the modified exosomes for treating cancers.
L'invention concerne des exosomes modifiés dérivés de cellules manquent sensiblement d'un ou plusieurs polypeptides immunosuppresseurs. L'invention concerne également des procédés de production d'exosomes modifiés et des méthodes d'utilisation de ces exosomes modifiés pour traiter les cancers.
Gercel-Taylor Cicek
Taylor Douglas D.
Gowling Lafleur Henderson Llp
University Of Louisville Research Foundation Inc.
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