Hig2 and urlc10 epitope peptide and vaccines containing the...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2734467

The present invention provides a pharmaceutical agent or composition containing one or more peptides having the amino acid sequence of SEQ ID NO: 1 or 2, or one or more polynucleotides encoding such a peptide formulated for the treatment and/or prevention of cancer in a subject whose HLA-A antigen is HLA-A0206. Furthermore, the present invention provides a method of inducing CTL and antigen-presenting cells using such peptides, polynucleotides or pharmaceutical agents.

La présente invention porte sur un agent pharmaceutique ou sur une composition contenant un ou plusieurs peptides possédant la séquence d'acides aminés de SEQ ID NO: 1 ou 2, ou un ou plusieurs polynucléotides codant pour un tel peptide formulé pour le traitement et/ou la prévention d'un cancer chez un sujet dont l'antigène HLA-A est HLA-A0206. De plus, la présente invention porte sur un procédé consistant à induire CTL et sur des cellules présentant un antigène qui utilisent de tels peptides, polynucléotides ou agents pharmaceutiques.

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