Process for diastereoselective conversion of chiral imines

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 209/26 (2006.01) C07C 209/52 (2006.01) C07C 209/62 (2006.01) C07C 211/07 (2006.01) C07C 211/27 (2006.01)

Patent

CA 2707813

Diastereo-selective conversion of chiral imines of formula (I) to amines of formula (I), (II), wherein the residuals R1 to R4 have the meaning given in the description and R1 and R2 are different to one another by the imine of formula (I) being converted in the presence of hydrogen and a heterogeneous catalyst containing copper.

L'invention concerne la transformation diastéréosélective d'imines chirales de formule (I) en amines de formule (I), (II), les radicaux R1 à R4 ayant la signification donnée dans la description et R1 et R2 étant différents l'un de l'autre. Selon l'invention, l'imine de formule (I) est transformée en présence d'hydrogène et d'un catalyseur hétérogène contenant du cuivre.

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