Compositions and methods for halogenation reactions

C - Chemistry – Metallurgy – 12 – N

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C12N 9/02 (2006.01) A01N 63/00 (2006.01) C07K 14/21 (2006.01) C12N 5/10 (2006.01) C12N 5/14 (2006.01) C12N 9/10 (2006.01) C12N 15/53 (2006.01) C12N 15/54 (2006.01) C12N 15/82 (2006.01) C12P 13/22 (2006.01) C12P 17/10 (2006.01) A01N 65/00 (2006.01)

Patent

CA 2393910

This invention describes methods, transgenic plants and transgenic microorganisms for the biosynthesis of halogenated natural products, where the halogenation is substrate and regiospecific. In particular, this invention relates to the use of halogenated metabolites, produced by the method of the invention, for the protection of host organisms against pathogens, more particularly, to the protection of plants against phytopathogens. In this aspect, the invention provides transgenic plants with enhanced resistance to phytopathogens, and biocontrol organisms with enhanced biocontrol properties.

L'invention porte sur des procédés des plantes transgéniques et des micro-organismes servant à la biosynthèse de produits naturels halogénés, l'halogénation étant spécifique à un substrat ou à une région. L'invention porte en particulier sur des métabolites halogénés (obtenus par le procédé de l'invention) servant à protéger des organismes hôtes contre des pathogènes et plus particulièrement des plantes contre des phytopathogènes. Dans ce dernier cas, l'invention porte sur des plantes transgéniques présentant une résistance accrue aux phytopathogènes, et sur des organismes de régulation biologique à propriétés améliorées de régulation biologique.

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