Slc1a1 antipsychotic drug response markers

Details Slc1a1 antipsychotic drug response markers Slc1a1 antipsychotic drug response markers

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2664366

Methods for predicting a subject's response to antipsychotic drug treatment by the steps of obtaining a biological sample from the subject, and determining the presence or absence of one or more polymorphisms in the SLC1A1 gene of the subject, wherein the presence of the one or more polymorphisms indicates that the subject's response to antipsychotic drug treatment. Also provided are kits for performing these methods.

La présente invention concerne des méthodes permettant de prédire la réponse d'un sujet à un traitement par un médicament antipsychotique, lesquelles méthodes consistent à prélever un échantillon biologique sur le sujet, puis à déterminer la présence ou l'absence d'un ou plusieurs polymorphismes dans le gène SLC1A1 du sujet, la présence d'un ou plusieurs polymorphismes indiquant que le sujet réagit à un traitement par un médicament antipsychotique. Cette invention concerne également des trousses permettant de mettre en oeuvre ces méthodes.

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