Compounds for protecting hydroxyls and methods for their use

Details Compounds for protecting hydroxyls and methods for their use Compounds for protecting hydroxyls and methods for their use

C - Chemistry, Metallurgy

07

H

C07H 19/06 (2006.01) C07H 19/10 (2006.01) C07H 19/16 (2006.01) C07H 19/20 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2386221

A hydrocarbyldithiomethyl-modified compound of the Formula (1): R1-O--CH2-S-S- R2, or a salt thereof wherein R1 is an organic molecule and R2 is a hydrocarbyl, is useful for protecting and/or blocking hydroxyl groups in organic molecules such as nucleotides. The hydrocarbyldithiomethyl-modified compounds can also be used for chemically synthesizing oligonucleotides and for sequencing nucleic acid compounds.

La présente invention concerne un composé modifié par hydrocarbyldithiométhyle de la formule (1) : R<1>-O--CH2-S-S-R<2>, ou un sel de ce dernier, dans laquelle R<1> est une molécule organique et R<2> est un hydrocarbyle, composé qui est utilisé pour protéger et/ou bloquer les groupes hydroxyles dans des molécules organiques telles que les nucléotides. Les composés modifiés par hydrocarbyldithiométhyle de l'invention peuvent également être utilisés dans la synthèse chimique des oligonucléotides et dans le séquençage des composés nucléotidiques.

Affiliated with

Also associated with

Rating

Compounds for protecting hydroxyls and methods for their use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds for protecting hydroxyls and methods for their use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds for protecting hydroxyls and methods for their use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1892843