Selective adsorption devices and systems

A - Human Necessities – 61 – M

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A61M 1/14 (2006.01) A61L 29/08 (2006.01) A61M 1/28 (2006.01) A61M 1/36 (2006.01) A61M 37/00 (2006.01) B01D 24/00 (2006.01) A61M 1/16 (2006.01)

Patent

CA 2471201

Intravenous, or indwelling, or integrated multi-functional devices and systems reduce levels of a targeted compound in blood by selective adsorption. The devices and systems can be used, e.g., to reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices and systems are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti- inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices and systems serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti- inflammatory stimulators or mediators.

L'invention concerne des dispositifs et systèmes multifonctionnels intraveineux, à demeure ou intégrés conçus pour réduire les concentrations sanguines d'un composant cible par adsorption sélective. Ces dispositifs et systèmes peuvent être utilisés, par exemple pour réduire les concentrations sanguines de stimulateurs ou médiateurs pro-inflammatoires ou anti-inflammatoires par adsorption sélective. Ces dispositifs et systèmes sont utiles dans des situations où des niveaux anormaux d'interactions non régulées ou excessives entre des stimulateurs ou des médiateurs pro-inflammatoires ou anti-inflammatoires sont atteints ou au cours d'événements induisant ou pouvant induire une production anormale de stimulateurs ou de médiateurs pro-inflammatoires ou anti-inflammatoires. Ces dispositifs et systèmes servent à prévenir, réguler, réduire ou atténuer la sévérité de la réponse inflammatoire et des états pathologiques associés à des niveaux anormaux d'interactions non régulées ou excessives entre des stimulateurs ou des médiateurs pro-inflammatoires ou anti-inflammatoires.

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