Transgenic animal expressing a multiple mutated form of...

A - Human Necessities – 01 – K

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Details

A01K 67/027 (2006.01) A61K 49/00 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2383982

The invention concerns the field of transgenic animal models and more particularly, animal models of Alzheimer disease. The invention relates to a transgenic animal expressing a multiple mutated form of presenilin 1 and enabling to detect an apoptotic phenomenon in a renewable peripheral tissue.

La présente invention concerne le domaine des modèles animaux transgéniques et plus particulièrement, les modèles animaux de la maladie d'Alzheimer. L'invention se rapporte à un animal transgénique exprimant une forme multi- mutée de la préséniline 1 et permettant de détecter un phénomène apoptotique dans un tissu périphérique renouvelable.

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