Mammalian elk potassium channel genes

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/00 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) C12N 5/16 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/554 (2006.01) G01N 33/566 (2006.01) G06F 17/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2341766

The present invention is directed to the isolation, cloning and sequencing of mammalian elk1, elk2, and EAG2 K channel genes. The amino acid sequences of the expressed proteins are also provided. Information on the distribution of the gene and their expression products in various relevant nervous system tissue is also provided. The gene and protein sequences and the distribution pattern information is helpful in the research and development of pharmaceuticals with specific action on the different K channels.

La présente invention concerne l'isolement, le clonage et le séquençage de gènes de mammifère elk1, elk2 et EAG2 à canal K. elle concerne également les séquences d'acides aminés des protéines ainsi exprimées. Cette invention renseigne par ailleurs sur la distribution de ces gènes et sur leurs produits d'expression dans divers tissus concernés du système nerveux. Les informations sur les séquences de gènes et de protéines et sur leur schéma de distribution sont utiles pour la recherche et la mise au point de produits pharmaceutiques ayant une action spécifique sur les différents canaux K.

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