Film comprising therapeutic agents

A - Human Necessities – 61 – K

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Details

A61K 31/21 (2006.01) A61K 9/70 (2006.01) A61K 47/30 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2530843

The present invention is related to the composition and methods of manufacture of orally-dissolvable, edible films as a vehicle for the non-invasive administration of nitroglycerin, as well as other therapeutic agents either with or without nitroglycerin, through the mucosal tissues of the oral cavity. The films include a water soluble film-forming polymer such as pullulan. Methods for producing the films are also disclosed.

La présente invention concerne la composition et des procédés de production de films comestibles à dissolution orale comme véhicule pour l'administration non invasive de nitroglycérine, ainsi que d'autres agents thérapeutiques avec ou sans nitroglycérine, à travers les tissus des muqueuses de la cavité buccale. Ces films renferment un polymère filmogène soluble dans l'eau, tel que le pullulane.

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