Use of skin penetration enhancers and barrier disruption...

A - Human Necessities – 61 – K

Patent

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A61K 39/39 (2006.01) A61K 9/00 (2006.01) A61K 9/70 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) A61K 39/02 (2006.01) A61K 39/106 (2006.01) A61K 47/08 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2321596

A transcutaneous immunization system where the topical application of an adjuvant and an antigen or nucleic acid encoding for an antigen, to intact skin induces a systemic or mucosal antibody response. The immune response so elicited can be enhanced by physical or chemical skin penetration enhancement.

Système d'immunisation transcutanée consistant à appliquer localement un adjuvant et un antigène ou un acide nucléique codant pour un antigène, à la peau intacte afin de provoquer une réponse immune systémique ou une réaction des muqueuses. On peut augmenter cette réponse immune par amplification physique ou chimique de la pénétration de la peau.

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