Condensed heterocyclic pyrazole derivatives as kinase...

Details Condensed heterocyclic pyrazole derivatives as kinase... Condensed heterocyclic pyrazole derivatives as kinase...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/4162 (2006.01) C07D 231/00 (2006.01) C07D 333/04 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2493680

Bicyclo-pyrazole compound of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, processes for their preparation, combinatorial libraries comprising a plurality of them and pharmaceutical compositions thereof, are herewith disclosed: the compounds of the invention are useful, in therapy, as protein kinase inhibitors, for instance in the treatment of cancer.

La présente invention concerne un composé bicyclo-pyrazolique représenté par la formule (I) et certains de ses sels pharmaceutiquement admis, conformément à la définition qu'en donne la spécification. L'invention concerne également des procédés permettant son élaboration, des échantillothèques combinatoires en comprenant une pluralité, et des compositions pharmaceutiques réalisées à partir de ces composés. Les composés de l'invention conviennent, à des fins thérapeutiques, comme inhibiteurs de protéines kinases, notamment pour le traitement du cancer.

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