Compositions and methods for genetic analysis of polycystic...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) A61K 31/7088 (2006.01) A61K 31/711 (2006.01) G01N 33/554 (2006.01)

Patent

CA 2403827

The subject invention relates to methods for detection of mutations in a PKD gene using DHPLC. The invention includes the following aspects:identification of PKD unique sites; design of PKD-specific primers; amplification of PKD-specific products; and analysis of PCR amplified products by DHPLC. The invention further relates to compositions such as identified unique sites and PKD-specific primers, and kits for performing the methods of the invention.

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