Methods of inhibiting smooth muscle cell proliferation and...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 35/00 (2006.01) A61K 38/17 (2006.01) C07H 21/04 (2006.01) C12N 15/63 (2006.01) C12N 15/86 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2347178

Methods of inhibiting vascular smooth muscle cell proliferation and preventing restenosis by transducing the vascular smooth muscle cells with a viral vector expressing RB2/p130 are provided.

L'invention concerne des procédés pour inhiber une prolifération des cellules du muscle lisse de la paroi vasculaire et empêcher la resténose, par transduction des cellules du muscle lisse de la paroi vasculaire au moyen d'un vecteur viral exprimant RB2/p130.

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