Automated packing system and method for chromatography columns

Details Automated packing system and method for chromatography columns Automated packing system and method for chromatography columns

G - Physics

01

N

G01N 30/50 (2006.01) B01D 15/20 (2006.01) G01N 30/52 (2006.01) G01N 30/56 (2006.01) B01D 15/12 (2006.01)

Patent

CA 2619818

A column packing system comprises a control unit provided with software for monitoring the column interior pressure and/or flow through the column for use in calculating the breakpoint where a movable adapter comes into contact with a consolidated bed of bed media. The calculated breakpoint is used by the control unit to determine how much further the movable adapter has to move into the column in order to achieve a desired amount of bed compression.

La présente invention se rapporte à un système de remplissage de colonne, qui comprend une unité de commande dotée d'un logiciel permettant de contrôler la pression intérieure de la colonne et/ou le débit à travers ladite colonne, ce qui permet de calculer le point d'arrêt, au niveau duquel un adaptateur mobile vient en contact avec un lit consolidé de matériaux de lit. Le point d'arrêt calculé est utilisé par l'unité de commande pour déterminer de combien un adaptateur mobile doit poursuivre son déplacement à l'intérieur de la colonne, afin que l'on obtienne une quantité désirée de compression de lit.

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