Method to identify immunocompromised patients at high risk...

Details Method to identify immunocompromised patients at high risk... Method to identify immunocompromised patients at high risk...

G - Physics

01

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G01N 33/564 (2006.01) C12P 19/04 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2189470

The present invention provides a method of identifying individuals who are at high risk for development of cryptococcosis, comprising the step of measuring the levels of IgG antibody to glucuronoxylomannan in the sera of said individuals. Also provided are various methods of detecting antibody to glucuronoxylomannan in sera and a kit for assaying the presence of antibody to glucuronoxylomannan in the sera of immunocompromised individuals.

Procédé d'identification d'individus présentant de forts risques de développement de cryptococcose consistant à mesurer le niveau des anticorps IgG contre le glucuronoxylomannane dans le sérum desdits individus. Elle porte également sur différents procédés de détection des anticorps contre le glucuronoxylomannane et sur un matériel de détection de la présence desdits anticorps dans le sérum d'individus à défenses immunitaires affaiblies.

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