C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/81 (2006.01) C12N 15/90 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/92 (2006.01)
Patent
CA 2100472
A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. These results suggest that APC is a tumor suppressor.
Albertsen Hans
Anand Rakesh
Carlson Mary L.
Groden Joanna L.
Hedge Philip John
Imperial Chemical Industries Plc
Sim & Mcburney
The Cancer Institute Of Japanese Foundation For Cancer Research
The Johns Hopkins University
The University Of Utah
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