Use of irl-1620 and paclitaxel for preventing and treating...

A - Human Necessities – 61 – K

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Details

A61K 38/16 (2006.01) A61K 31/28 (2006.01) A61K 31/337 (2006.01) A61K 31/4745 (2006.01) A61K 31/519 (2006.01) A61K 31/704 (2006.01) A61K 33/24 (2006.01) A61K 38/17 (2006.01) A61K 38/20 (2006.01) A61K 38/21 (2006.01) A61K 38/22 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2502848

Compositions and methods of preventing or treating a breast cancer are disclosed. The composition and method can utilize an endothelin B agonist and a chemotherapeutic agent as active ingredients to treat a solid tumor in mammals, including humans. Alternatively, the composition and method can utilize an endothelin B antagonist and an optional angiogenesis inhibitor to treat a solid tumor in mammals, including humans.

L'invention concerne des compositions et des méthodes destinées à la prévention et au traitement d'un cancer du sein. Cette composition et cette méthode peuvent faire intervenir un agoniste de l'endothéline B et un agent chimiothérapeutique comme ingrédients actifs pour traiter une tumeur solide chez des mammifères, y compris des êtres humains. Cette composition et cette méthode peuvent également faire intervenir un antagoniste de l'endothéline B et éventuellement un inhibiteur de l'angiogenèse pour traiter une tumeur solide chez des mammifères, y compris des êtres humains.

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