Therapeutic polypeptides, nucleic acids encoding same, and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2455389

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention concerne des séquences d'acides nucléiques codant des nouveaux polypeptides. L'invention concerne également des polypeptides codés par ces séquences d'acides nucléiques et des anticorps se liant de manière immunospécifique au polypeptide, ainsi que des dérivés, des variants, des mutants ou des fragments du nouveau polypeptide, de polynucléotide ou d'anticorps spécifique au polypeptide. L'invention concerne également des vecteurs, des cellules hôtes, des anticorps et des procédés de recombinaison permettant d'obtenir les polypeptides et polynucléotides, ainsi que des procédés d'utilisation de ceux-ci. L'invention concerne enfin des procédés thérapeutiques, diagnostiques et de recherche destinés au diagnostic, au traitement et à la prévention de troubles mettant en oeuvre un acide nucléique quelconque ou une protéine quelconque parmi ces nouveaux acides nucléiques et protéines humains.

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