Therapeutic pyrazolo[3,4-b] pyridines and indazoles

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 471/04 (2006.01) A61K 31/416 (2006.01) A61K 31/4162 (2006.01) A61P 25/00 (2006.01) C07D 231/56 (2006.01)

Patent

CA 2588812

The present invention provides for compounds of Formula (I): wherein R2, R3, R4, R5, R6, R7,X, and L have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of central nervous disorders and conditions including attention deficit hyperactivity disorder, neuropathic pain, urinary incontinence, anxiety, depression, and schizophrenia and fibromyalgia. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (I).

La présente invention concerne des composés de formule (I), dans laquelle R2, R3, R4, R5, R6, R7,X, et L représentent une des valeurs définies dans la spécification, et des sels acceptables pharmaceutiquement associés, qui sont utilisés en tant qu'agents dans le traitement de troubles du système nerveux central et d'autres troubles, y compris, le trouble d'hyperactivité avec déficit de l'attention, une douleur neuropathique, l'incontinence urinaire, l'anxiété, la dépression, la schizophrénie et la fibromyalgie. Cette invention a aussi pour objet des compositions pharmaceutiques renfermant au moins un composé de la formule (I).

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