Materials and methods for introducing genetic material into...

Details Materials and methods for introducing genetic material into... Materials and methods for introducing genetic material into...

C - Chemistry, Metallurgy

08

G

C08G 79/04 (2006.01) A61K 47/34 (2006.01) C08G 18/32 (2006.01) C08G 18/42 (2006.01) C08G 18/48 (2006.01) C08G 18/66 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2669846

The present invention generally relates to introducing genetic material to living cells. In some embodiments, the present invention relates to compositions of matter for targeted delivery of nucleic acids to cells. In other embodiments, the present invention relates to methods of targeted delivery of nucleic acids to cells. In still other embodiments, the present invention relates to polymers that contain at least one amino acid in their backbone. In yet other embodiments, the present invention relates to polymers that contain at least one amino acid in their backbone thereby resulting in biodegradability, and in some embodiments, controlled biodegradability.

La présente invention concerne de manière générale l'introduction de matériau génétique dans des cellules vivantes. Dans certains modes de réalisation, la présente invention concerne des compositions de substances destinées à la libération ciblée d'acides nucléiques dans des cellules. Dans d'autres modes de réalisation, la présente invention concerne des procédés destinés à la libération ciblée d'acides nucléiques dans des cellules. Dans d'autres modes de réalisation encore, la présente invention concerne des polymères dont le squelette comprend au moins un acide aminé. Dans d'autres modes de réalisation encore, la présente invention concerne des polymères dont le squelette comprend au moins un acide aminé, ce qui leur attribue une propriété de biodégradabilité et, dans certains modes de réalisation, de biodégradabilité contrôlée.

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