Process for the preparation of tablets comprising...

A - Human Necessities – 61 – K

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A61K 9/28 (2006.01) A61K 31/198 (2006.01) A61K 31/7076 (2006.01)

Patent

CA 2461576

There is described a process for the preparation of tablets comprising S- adenosylmethionine which comprises blending S-adenosylmethionine with calcium sulfate and/or phosphate, calcium and/or magnesium carbonate, glycerol behenate and or palmitostearate and silica and compressing the resulting mixture. The tablets obtainable by the process of the invention are stable and show a low relative humidity and hygroscopicity.

L'invention concerne un procédé de préparation de comprimés de S-adénosylméthionine comportant un mélange de S-adénosylméthionine avec du sulfate de calcium et/ou du phosphate de calcium, du carbonate de calcium et/ou de magnésium, du glycérol béhénate et/ou du palmitostéarate et du silice. Le résultat dudit mélange est alors comprimé, formant ainsi des comprimés stables et présentant une humidité et une hygroscopicité relatives.

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