C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/09 (2006.01) A61K 39/40 (2006.01) C07K 14/195 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) C12Q 1/14 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2411927
The GapC plasmin binding protein genes of Streptococcus dysgalactiae (S. dysgalactiae), Streptococcus agalactiae (S. agalactiae), Streptococcus uberis (S. uberis), Streptococcus parauberis (S. parauberis), and Streptococcus iniae (S.iniae) are described, as well as the recombinant production of the GapC proteins therefrom. Also described is the use of the GapC proteins from those species in vaccine compositions to prevent or treat bacterial infections in general, and mastitis in particular.
L'invention concerne les gènes de la protéine GapC de liaison de la plasmine de <i>Streptococcus dysgalactiae (S. dysgalactiae), Streptococcus agalactiae (S.agalactiae), Streptococcus uberis (S.uberis), Streptococcus parauberis (S.parauberis) et Streptococcus iniae (S.iniae)</i>, ainsi que la production recombinante des protéines GapC à partir de ces gènes. L'invention concerne également l'utilisation des protéines GapC à partir de ces différentes espèces dans des compositions vaccinales pour prévenir ou traiter des infections bactériennes en général, et la mammite en particulier.
Bolton Alexandra J.
Fontaine Michael
Perez-Casal Jose
Potter Andrew A.
Gowling Lafleur Henderson Llp
University Of Saskatchewan
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