A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/06 (2006.01) A61K 38/08 (2006.01) A61P 3/00 (2006.01) A61P 3/08 (2006.01)
Patent
CA 2603452
The present invention relates to the use of a regulatory protein RS1 fragment or a nucleic acid molecule encoding said regulatory protein RS1 fragment for the preparation of a pharmaceutical composition for the amelioration, prevention and/or treatment of a metabolic disease or a secondary disorder caused by a (pathological) modification of homeostasis, wherein said RS1 fragment is characterized in comprising at least the amino acid sequence Q-C-P (Glutamine-Cysteine-Proline) or derivatives thereof. Furthermore, the present invention relates to a method for the amelioration, prevention and/or treatment of a metabolic disease or a secondary disorder caused by a (pathological) modification of homeostasis, said method comprising administering to a patient in need of such amelioration, prevention and/or treatment a pharmaceutically active amount of a regulatory protein RS1 fragment or a nucleic acid molecule encoding a regulatory protein RS1 fragment, wherein said RS1 fragment is characterized in comprising at least the amino acid sequence Q-C-P (Glutamine-Cysteine-Proline) or derivatives thereof. Moreover, the present invention relates to the use of a regulatory protein RS1 fragment or a nucleic acid molecule encoding said regulatory protein RS1 fragment for the preparation of food and/or food supplements.
La présente invention concerne l'utilisation du fragment RS1 d'une protéine régulatrice ou d'une molécule d'acide nucléique codant ledit fragment RS1 d'une protéine régulatrice pour l'élaboration d'une composition pharmaceutique visant à l'amélioration, la prévention et/ou le traitement d'une affection du métabolisme ou d'un trouble secondaire provoqué par une modification (pathologique) de l'homéostasie. Ce fragment RS1 est caractérisé en ce qu'il comprend au moins la séquence d'acide aminé Q-C-P (Glutamine-Cysteine-Proline) ou de certains de leurs dérivés. L'invention concerne en outre un procédé visant à l'amélioration, la prévention et/ou le traitement de ces mêmes maladies et troubles. Ce procédé consiste en l'administration, à un patient justifiant d'un tel traitement, d'une quantité suffisante du fragment RS1 de protéine régulatrice de l'invention ou d'une molécule d'acide nucléique codant ce fragment. L'invention concerne enfin l'utilisation de ces fragments ou molécule pour l'élaboration de produits alimentaires et/ou de suppléments alimentaires.
Koepsell Hermann
Vernaleken Alexandra
Goudreau Gage Dubuc
Julius-Maximillians-Universitat Wurzburg
LandOfFree
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