Bacterial process for the resolution of racemic cis-diols

C - Chemistry – Metallurgy – 12 – P

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C12P 41/00 (2006.01)

Patent

CA 2199159

A process for resolution of a mixture of dihydroxydihydroindene enantiomers comprising treating the mixture of enantiomers with a Pseudomonas putida species microorganism. Resolved dihydroxydihydroindenes are valuable intermediates for the synthesis of biologically active compounds such as pharmaceuticals and agrochemicals.

Procédé de dédoublement d'un mélange d'énantiomères de dihydroxydihydroindène consistant à traiter ce mélange avec un micro-organisme de l'espèce Pseudomonas putida. Les dihydroxydihydroindènes dédoublés constituent des intermédiaires précieux dans la synthèse de composés actifs sur le plan biologique, tels que des agents pharmaceutiques et agrochimiques.

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