Enzymatic resolution of a racemic mixture of stereospecific...

C - Chemistry – Metallurgy – 12 – P

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C12P 41/00 (2006.01) C12P 13/00 (2006.01)

Patent

CA 2136840

The present invention relates to the enzymatic resolution of a racemic mixture of stereospecific, pharmaceutically useful in vivo inhibitors of .gamma.-aminobutyric acid transaminase (GABA-T), specifically .gamma.-ethynyl GABA, .gamma.-vinyl GABA and .gamma.-allenyl GA- BA using penicillin acylase (PA).

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