Pharmaceutical compositions containing acrylic acid...

A - Human Necessities – 61 – K

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A61K 31/255 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) A61K 31/275 (2006.01)

Patent

CA 2021051

PHARMACEUTICAL COMPOSITIONS CONTAINING ACRYLIC ACID DERIVATIVES AND THEIR USE IN THE MEDICINE A b s t r a c t o f t h e d i s c l o s u r e Known acrylic acid derivatives of formula Image (I) wherein n is an integer of from 0 to 2, R represents a hydrogen, an alkaline or an alkaline earth metal atom, or a C1-4alkyl group, and R1 represents a hydrogen or a halogen atom or a C1-4- alkyl, a C1-4alkoxy or a nitro group. have useful pharmaceutical activities, in particular cytoprotective and optionally antiulcer activities. They can be used in the treatment and prevention of ulceration in the digestive tract of mammals, inclusive men.

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