Expression receptors with 7 transmembrane domains in...

Details Expression receptors with 7 transmembrane domains in... Expression receptors with 7 transmembrane domains in...

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2492977

The invention concerns the expression in a baculovirus-insect cell system of receptors with seven transmembrane domains, in particular receptors coupled to proteins G, in particular olfactory receptors, under the transcriptional control of a promoter derived from the polyhedrin promoter by deletion of all or part of the region of said promoter extending from -1 to -12 positions relative to the initiation site of the polyhedrin translation.

ABREGELa présente Invention concerne l'expression dans un système baculovirus/cellule d'insecte de récepteurs à sept domaines transmembranaires, notamment de récepteurs couplés aux protéines G, en particulier de récepteurs olfactifs, sous le contrôle transcriptionnel d'un promoteur dérivé du promoteur de la polyédrine par délétion de tout ou partie de la région dudit promoteur s'étendant des positions -1 à -12 par rapport au site d'initiation de la traduction de la polyédrine.

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