Composition and method to increase mammalian sperm function

Details Composition and method to increase mammalian sperm function Composition and method to increase mammalian sperm function

C - Chemistry, Metallurgy

07

K

C07K 14/81 (2006.01) C07K 14/47 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2643413

A composition of matter for increasing the motility and/or percentage of intact acrosomes (PIA) in sperm is described. The composition includes, in combination, an amount of FAA and an amount of TIMP-2, wherein the amounts are effective to increase the motility, the PIA, or the motility and PIA of sperm contacted with the composition. The composition can be used as a cryopreservation medium for sperm.

La présente invention concerne une composition destinée à augmenter la motilité et/ou le pourcentage d~acrosomes intacts (PIA) dans du sperme. Cette composition comprend, en association, une quantité de FAA et une quantité de TIMP-2, les quantités étant efficaces pour augmenter la motilité, le PIA, ou la motilité et le PIA du sperme en contact avec la composition. La composition peut être utilisée en tant que un milieu de cryoconservation pour du sperme.

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