P38 inhibitors and methods of use thereof

Details P38 inhibitors and methods of use thereof P38 inhibitors and methods of use thereof

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/416 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2647949

Compounds of formula (I): in which A, B, X, Ar1, R8 and R4 have any of the meanings given in the specification, are inhibitors of p38 useful in the treatment and prevention of various disorders mediated by p38.

Les composés de formule (I) : où A, B, X, Ar1, R8 et R4 ont l'une quelconque des valeurs données dans la description, sont des inhibiteurs de p38 qui peuvent être employés dans le traitement prophylactique et thérapeutique de divers troubles faisant intervenir p38.

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