Substituted amidoalkyl-uracils as parp inhibitors

Details Substituted amidoalkyl-uracils as parp inhibitors Substituted amidoalkyl-uracils as parp inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/96 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 9/10 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 411/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 487/04 (2006.01) C07D 495/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2416036

The invention relates to novel PARP inhibitors in the form of amidoalkyl- uracil derivatives of formula (I), to a method for producing them and to their use as active agents of medicaments, for preventing and/or treating ischaemia and reperfusion damage.

L'invention concerne de nouveaux inhibiteurs de PARP sous forme de dérivés d'amidoalkyle-uracile de formule (I), un procédé permettant de les préparer et leur utilisation comme principes actifs de médicaments pour assurer la prophylaxie et/ou le traitement de lésions dues à l'ischémie et à la reperfusion.

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