Process for treating protein solutions

Details Process for treating protein solutions Process for treating protein solutions

C - Chemistry, Metallurgy

07

K

C07K 1/34 (2006.01) A23J 1/20 (2006.01)

Patent

CA 2146720

An improvement is provided in a process for the membrane filtration of a protein solution. The improvement consists of applying a high shear force at the surface of the membrane. The membrane filtration utilizes a rotating membrane disc mounted in close proximity to a stationary solid (i.e., unapertured) disc, or a rotating solid (i.e., unapertured) disc mounted in close proximity to a stationary membrane surface. The rotation is at a speed of between 1,000 and 3,450 RPM, and the close proximity is defined by a space therebetween of 1/8" to 1/4". This results in permeation characteristics of the selected membrane which essentially represents its theoretical molecular weight cut-off.

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