A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/12 (2006.01) A61K 31/46 (2006.01)
Patent
CA 2531847
This invention relates to stable pharmaceutical solution formulations suitable for aerosol administration containing an anticholinergic of formula (I) wherein X- is a pharmaceutically acceptable anion. More particularly, this invention relates to stable pharmaceutical solution formulations suitable for aerosol administration containing an anticholinergic of formula (I) in an environmentally safe hydrofluorocarbon (HFC) as a propellant, together with an organic compound as a cosolvent wherein either an inorganic acid or an organic acid is added to the aerosol solution formulation.
Cette invention concerne des formes pharmaceutiques en solution stables pouvant être administrées sous forme d'aérosol, qui contiennent un anticholinergique de formule (I), dans laquelle X?-¿ est un anion pharmaceutiquement acceptable. Plus particulièrement, l'invention concerne des formes pharmaceutiques en solution stables pouvant être administrées sous forme d'aérosol, qui contiennent un anticholinergique de formule (I) présent dans un pentafluoroéthane (HFC) écologiquement sûr utilisé comme propulseur, en association avec un composé organique utilisé comme cosolvant, un acide inorganique ou acide organique étant ajouté à la forme de pulvérisation en solution.
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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