Compositions and methods for increasing blood platelet...

Details Compositions and methods for increasing blood platelet... Compositions and methods for increasing blood platelet...

A - Human Necessities

61

K

A61K 31/496 (2006.01) A61K 9/20 (2006.01) A61P 7/00 (2006.01)

Patent

CA 2660283

Disclosed in certain embodiments is an oral pharmaceutical dosage form comprising a pharmaceutically acceptable excipient and an effective amount of l-(3- chloro-5- {[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin- 1 -yl)thiazol-2-yl] carbamoyl} pyridin-2-yl)piperadine-4-carboxylic acid (Formula I) or a pharmaceutically acceptable salt thereof, to increase platelet levels in humans.

La présente invention porte dans certains modes d'application sur une forme galénique orale comprenant un excipient de qualité pharmaceutique et une quantité active d'acide 1-(3-chloro-5-{[4-(4-chlorothiophén-2-yl)-5-(4-cyclohexylpipérazin-1-yl)thiazol-2-yl]carbamoyl}pyridin-2-yl)pipéradine-4-carboxylique (Formule I) ou un sel de qualité pharmaceutique dudit composé, utilisée pour augmenter la concentration en plaquettes chez l'homme.

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