Artificial chromosomes comprising ehv sequences

Details Artificial chromosomes comprising ehv sequences Artificial chromosomes comprising ehv sequences

C - Chemistry, Metallurgy

12

N

C12N 15/70 (2006.01) A61K 39/245 (2006.01) A61K 48/00 (2006.01) C07K 14/03 (2006.01) C12N 7/00 (2006.01) C12N 7/04 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2443039

The invention belongs to the field of animal health, in particular equine diseases caused by equine herpesvirus (EHV). The invention relates to artificial chromosomes comprising the genome of equine herpesviruses, methods of producing attenuated or virulent EHV with or without the insertion of foreign genes, EHV obtainable with said methods and pharmaceutical compositions comprising said viruses.

La présente invention a trait au domaine de la santé animale et concerne plus particulièrement les maladies équines provoquées par l'herpès-virus équin (EHV). L'invention se rapporte à des chromosomes artificiels comportant le génome d'herpès-virus équins, des méthodes de production d'un EHV virulent ou atténué pouvant comprendre l'insertion de gènes étrangers, l'EHV que permettent de produire lesdites méthodes ainsi qu'à des compositions pharmaceutiques contenant lesdits virus.

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